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Clostridium and augmentin

Augmentin, Augmentin XR Back to Top The term antibiotic-associated diarrhea (AAD) refers to a benn, self-limited diarrhea following the use of antimicrobials. Medscape - Indication-specific dosing for Augmentin, Augmentin XR amoxicillin/clavulanate, frequency-based adverse effects, comprehensive

Drug Safety Labeling Changes Augmentin amoxicillin/clavulanate. It's used to treat bacterial infections in your airways, such as a sinus infection or pneumonia. Clostridium difficile associated diarrhea CDAD has been reported with use of nearly all antibacterial agents, including Augmentin, and may range in severity.

Reference ID 3248650 Β-lactamase−producing strains of Haemophilus influenzae and Moraxella catarrhalis Mild to moderate: 500/125 mg PO q12hr or 250/125 mg PO q8hr for 10 days Severe: 875/125 mg PO q12hr or 500/125 mg PO q8hr or 2000 mg (2 extended-release tabs) PO q12hr for 7-10 days Take with meals to avoid GI upset Take suspension at start of meal to enhance absorption Dysphagia: May substitute 250 mg/5 m L suspension for 500/125 mg tablet; may substitute 200 mg/5 m L or 400 mg/5 m L suspension for 875/125 mg tablet Because of the different amoxicillin-to-clavulanate ratios in the 250-mg tablet (amoxicillin 250 mg, clavulanate125 mg) and the 250-mg chewable tablet (amoxicillin 250 mg, clavulanate 62.5 mg), the 250-mg tablet should not be used if the pediatric patient wehs Hypersensitivity reactions Anaphylaxis Anemia Thrombocytopenia Leukopenia Agranulocytosis Hepatoxicity AST/ALT elevation Pseudomembranous colitis Serum sickness Abdominal discomfort Cholestatic jaundice Flatulence Allergy to cephalosporins, carbapenems Different tablets are not interchangeable, because ratios of amoxicillin to clavulanate are different Extended release tablets not for use in renal impairment (Cr Cl Amoxicillin binds to penicillin-binding proteins, thus inhibiting final transpeptidation step of peptidoglycan synthesis in bacterial cell walls; addition of clavulanate inhibits beta-lactamase-producing bacteria, allowing amoxicillin extended spectrum of action It is a semisynthetic antibiotic with a broad spectrum of bactericidal activity, covering both gram-negative and gram-positive microorganisms Not effective against Mycoplasma and Legionella spp Peak plasma time: 2 hr (amoxicillin); 1.1 hr (clavulanic acid) Peak concentration: 8-22 mcg/m L (amoxicillin); 0.8-2.6 mcg/m L (clavulanic acid) AUC: 40-80 mcg•hr/m L (amoxicillin); 2-6 mcg•hr/m L (clavulanic acid) The above information is provided for general informational and educational purposes only. Augmentin PLR Master FULL PRESCRIBING INFORMATION. 1. INDICATIONS AND USAGE. To reduce the development of drug-resistant bacteria and maintain the

Augmentin Dosage, Side Effects & Uses - Individual plans may vary and formulary information changes. Emphasizes the medications amoxicillin and clavulanic acid Amoclan, Augmentin, Augmentin XR, Augmentin ES-600, which are drugs used against many various

Augmentin - FDA prescribing information, Augmentin is the brand name of a combination antibiotic drug containing amoxicillin and clavulanate potassium. Augmentin official prescribing information for healthcare professionals. Includes indications, dosage, adverse reactions, pharmacology and more.


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